Trial Parameters
Condition Celiac Disease
Sponsor Institut National de la Santé Et de la Recherche Médicale, France
Study Type OBSERVATIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2020-02-27
Completion 2030-02-27
All Conditions
Interventions
Blood sample collection; gastrointestinal biopsy
Brief Summary
The study focuses the mechanisms underlying the loss of intestinal homeostasis in celiac disease, refractory celiac disease and other immune diseases such as monogenic enteropathy, inflammatory bowel diseases or drug induced intestinal diseases. Mechanisms of transformation of lymphocytes leading to onset of lymphomatous complications of immune enteropathies will be investigated. Mechanisms of loss of hepatic lymphocytic homeostasis will also be assessed in liver associated diseases.
Eligibility Criteria
Inclusion Criteria: * 18 years or over * affiliated to social insurance * signed informed consent Exclusion Criteria: * pregnancy * under guardianship * not able to sign informed consent
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