← Back to Clinical Trials
Recruiting NCT05440448

NCT05440448 Patch-free Occlusion Therapy

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05440448
Status Recruiting
Phase
Sponsor Retina Foundation of the Southwest
Condition Amblyopia
Study Type INTERVENTIONAL
Enrollment 68 participants
Start Date 2024-04-22
Primary Completion 2028-01-31

Eligibility & Interventions

Sex All sexes
Min Age 3 Years
Max Age 12 Years
Study Type INTERVENTIONAL
Interventions
Patch-free occlusion therapyAdhesive patch

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 68 participants in total. It began in 2024-04-22 with a primary completion date of 2028-01-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of the study is to determine whether a patch-free occlusion therapy leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is associated with better adherence to the treatment.

Eligibility Criteria

Inclusion Criteria: * 3-12 years * male and female * strabismic, anisometropic, or combined mechanism amblyopia (visual acuity: 0.3-0.8 logMAR) * interocular visual acuity difference ≥0.3 logMAR * wearing glasses (if needed) for a minimum of 8 weeks with no change in visual acuity at 2 visits ≥4 weeks apart * child's ophthalmologist and family willing to forgo standard patching treatment during the study Exclusion Criteria: * Prematurity ≥8 wk * coexisting ocular or systemic disease * developmental delay * myopia \> -3.00D

Contact & Investigator

Central Contact

Eileen E Birch, PhD

✉ ebirch@retinafoundation.org

📞 2143633911

Frequently Asked Questions

Who can join the NCT05440448 clinical trial?

This trial is open to participants of all sexes, aged 3 Years or older, up to 12 Years, studying Amblyopia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05440448 currently recruiting?

Yes, NCT05440448 is actively recruiting participants. Contact the research team at ebirch@retinafoundation.org for enrollment information.

Where is the NCT05440448 trial being conducted?

This trial is being conducted at Dallas, United States.

Who is sponsoring the NCT05440448 clinical trial?

NCT05440448 is sponsored by Retina Foundation of the Southwest. The trial plans to enroll 68 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology