NCT05962164 Passive Heat Therapy for People With COPD
| NCT ID | NCT05962164 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of British Columbia |
| Condition | COPD |
| Study Type | INTERVENTIONAL |
| Enrollment | 32 participants |
| Start Date | 2023-08-17 |
| Primary Completion | 2026-05-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 32 participants in total. It began in 2023-08-17 with a primary completion date of 2026-05-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
People with Chronic Obstructive Pulmonary Disease (COPD) often develop high blood pressure and heart disease due to their sedentary lifestyle and difficulty exercising. The investigators will test if heating can mimic the health benefits of exercise by monitoring the increase in leg blood-flow using ultrasound during a 45-minute hot-water footbath. The patients will then undergo 6-weeks of hot-water footbaths to examine whether the changes to blood-flow lead to improvements in blood pressure and other indicators of heart disease risk.
Eligibility Criteria
Inclusion Criteria: * Non-smoking individuals * \>40 years of age * Stable (exacerbation free for \>6 weeks), moderate-to-severe COPD (post bronchodilator FEV1/FVC \<lower limit of normal and FEV1 z-score \<2.51) Exclusion Criteria: * Performing structured exercise training (i.e. pulmonary rehabilitation) * Have advanced cardiac or cerebrovascular disease (i.e. a history of heart failure, previous stroke or myocardial infarction) * Have uncontrolled hypertension (\>160/95 mmHg at rest) * Have hypotension (\<110/60 mmHg) * Are taking Beta Blockers * Regularly (\>1/week) have hot baths (\>30 min) or use a hot tub or sauna. Exclusion Criteria for exercise outcomes: * Have resting blood pressure \> 150/95 mmHg * On supplemental oxygen for hypoxemia. * Musculoskeletal pain that limits their ability to perform stationary cycling.
Contact & Investigator
Neil Eves, PhD
PRINCIPAL INVESTIGATOR
Associate Professor
Frequently Asked Questions
Who can join the NCT05962164 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, studying COPD. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05962164 currently recruiting?
Yes, NCT05962164 is actively recruiting participants. Contact the research team at neil.eves@ubc.ca for enrollment information.
Where is the NCT05962164 trial being conducted?
This trial is being conducted at Kelowna, Canada.
Who is sponsoring the NCT05962164 clinical trial?
NCT05962164 is sponsored by University of British Columbia. The principal investigator is Neil Eves, PhD at Associate Professor. The trial plans to enroll 32 participants.
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