NCT06438419 Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
| NCT ID | NCT06438419 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital, Bordeaux |
| Condition | Parkinson Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2025-04-16 |
| Primary Completion | 2027-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2025-04-16 with a primary completion date of 2027-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Expression of hypokinetic and hyperkinetic motor symptoms in Parkinson's disease (PD) is associated with pathological synchronous oscillations of neuronal activity (local field potential/LFP) in the cortico-subcortical network with a wide frequency range. In the present project, we propose to study cortico-subcortical oscillations and their synchronization in patients operated for PD (subthalamic deep brain stimulation (STN-DBS)) during distinct pharmacological and stimulation conditions (hypokinetic and hyperkinetic), using a simple motor task.
Eligibility Criteria
Inclusion Criteria: * Male or Female * 18 to 75 years-old * With idiopathic Parkinson's disease * Having a STN-DBS with a PERCEPT™ for less than a year or being candidate for STN-DBS with the PERCEPT™ device (first-implantation) * Able to perform the simple motor task * Patients covered by a health insurance scheme * Giving free, informed, written consent signed by the participant and the investigator. Exclusion Criteria: * Be incapable of giving consent personally. * Be subject to a legal protection measure (curatorship, guardianship) or be placed under judicial protection. * Being pregnant or breastfeeding * Present a serious and/or decompensated somatic or psychiatric illness.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06438419 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06438419 currently recruiting?
Yes, NCT06438419 is actively recruiting participants. Contact the research team at dominique.guehl@chu-bordeaux.fr for enrollment information.
Where is the NCT06438419 trial being conducted?
This trial is being conducted at Bordeaux, France.
Who is sponsoring the NCT06438419 clinical trial?
NCT06438419 is sponsored by University Hospital, Bordeaux. The trial plans to enroll 20 participants.
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