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Recruiting NCT07143695
Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion
Trial Parameters
Condition Critically Ill
Sponsor Cairo University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 200
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2025-09-01
Completion 2026-08-01
Interventions
Parasternal intercostal thickening fractionSham parasternal intercostal thickening
Brief Summary
Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.
Eligibility Criteria
Inclusion Criteria: * critically ill patient mechanically ventilated for 24 hours or more first spontaneous breathing trial Exclusion Criteria: * patient refusal difficult ultrasound views tracheostomized patient neuromuscular disorders