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Recruiting Phase 4 NCT07773155

NCT07773155 Pain Control With Ketorolac and Nerve Block After Wrist and Hand Surgery

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Clinical Trial Summary
NCT ID NCT07773155
Status Recruiting
Phase Phase 4
Sponsor University of Chicago
Condition Surgery, Upper Extremity
Study Type INTERVENTIONAL
Enrollment 120 participants
Start Date 2025-03-17
Primary Completion 2027-02

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
ToradolOxycodone

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.

This trial targets 120 participants in total. It began in 2025-03-17 with a primary completion date of 2027-02.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to learn about the effectiveness of different pain control options after hand and wrist surgery, specifically Ketorolac, Tylenol, and a regional nerve block. Ketorolac (Toradol) is a nonsteroidal anti-inflammatory drug (NSAID) that is similar to ibuprofen (Motrin or Advil). Tylenol (acetaminophen) is a commonly used over the counter drug. A nerve block is pain medication that is applied directly to the nerves around the surgical site before the surgery and keeps working to reduce pain in the area for several hours after the surgery. All of these medicines and procedures are approved by the Food and Drug Administration (FDA) for patient care. This study aims to understand if using these medicines in combination helps patients having hand and wrist surgery avoid the need for opioid pain medications.

Eligibility Criteria

Inclusion Criteria: 1. Age 18 years or older 2. Undergoing upper extremity surgery performed by a hand and upper extremity orthopaedic surgeon at the University of Chicago. 3. Undergoing procedure with regional nerve block Exclusion Criteria: 1. Age less than 18 years 2. Concomitant chronic opioid use 3. Postoperative opioid use (surgery through POD 14) for condition other than repaired fracture 4. Medical contraindication to ketorolac use, including pregnancy 5. Undergoing multiple concurrent surgical procedures 6. Unable to communicate numerical pain score

Contact & Investigator

Central Contact

Jennifer Wolf, MD

✉ jwolf@bsd.uchicago.edu

📞 773-795-3583

Frequently Asked Questions

Who can join the NCT07773155 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Surgery, Upper Extremity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07773155 trial and what does that mean for participants?

Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.

Is NCT07773155 currently recruiting?

Yes, NCT07773155 is actively recruiting participants. Contact the research team at jwolf@bsd.uchicago.edu for enrollment information.

Where is the NCT07773155 trial being conducted?

This trial is being conducted at Chicago, United States.

Who is sponsoring the NCT07773155 clinical trial?

NCT07773155 is sponsored by University of Chicago. The trial plans to enroll 120 participants.

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