Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients
Trial Parameters
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Brief Summary
Malnutrition is common in surgical patients. Many studies have shown a clear association between malnutrition and poor surgical outcomes. Parenteral nutrition (PN) is a nutrition intervention that is given by vein and can be safely provided to malnourished patients. It contains carbohydrates, fats, and protein just like you would normally in your diet. Pre-operative PN is able to improve outcomes in surgical patients. However, pre-operative PN has traditionally required hospital admission which results in increased length of stay, hospital cost, and hospital-acquired infection. Moreover, in hospital pre-operative PN may not be feasible or prioritized when access to inpatient surgery beds is limited. Outpatient PN provides the opportunity to solve this problem. The feasibility and impact of outpatient PN in malnourished patients undergoing major surgery have not previously been studied. This study aims to evaluate the feasibility of outpatient pre-operative PN and its effect on patient's outcomes.
Eligibility Criteria
Inclusion Criteria: 1. Patients 18 years of age or older 2. Patients screened at risk of malnutrition by Canadian Nutrition Screening Tool (CNST) and identified as malnourished by subjective global assessment (SGA) B or C Exclusion Criteria: 1. Patients undergoing minor or laparoscopic surgery 2. Pregnancy 3. Patients with severe systemic diseases defined by American Society of Anesthesiologists (ASA) classification III to V 4. Patients with diabetes mellitus 5. Patients with planned palliative treatment