NCT05989386 Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
| NCT ID | NCT05989386 |
| Status | Recruiting |
| Phase | Phase 2, Phase 3 |
| Sponsor | Dow University of Health Sciences |
| Condition | Surgical Site Infection |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2023-04-29 |
| Primary Completion | 2025-09-29 |
Trial Parameters
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
Brief Summary
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
Eligibility Criteria
Inclusion Criteria: * • Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi * The age of patients should be between 18-60 years old. Exclusion Criteria: * Diabetic patients * Immune-suppressed patients * Patients taking steroids * Patients undergoing chemo-radiotherapy. * Pregnant females * Previous abdominal surgery within the last 30 days. * Presence of concurrent abdominal wall infections. * Trauma Laparotomies * Large Bowel perforations