NCT07748676 Outcome of Partial Pulpotomy in Permanent Mandibular Molars With Symptomatic Irreversible Pulpitis After Wound Lavage With Calcium Hypochlorite or Sodium Hypochlorite
| NCT ID | NCT07748676 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Postgraduate Institute of Dental Sciences Rohtak |
| Condition | Symptomatic Irreversible Pulpitis (SIP) |
| Study Type | INTERVENTIONAL |
| Enrollment | 106 participants |
| Start Date | 2026-04-29 |
| Primary Completion | 2027-10-28 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 106 participants in total. It began in 2026-04-29 with a primary completion date of 2027-10-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this randomised control trial is to compare the effect of wound lavage using 2.5% Ca(OCl)₂ and 2.5% NaOCl on the outcome of partial pulpotomy in mature permanent mandibular molars with symptomatic irreversible pulpitis (SIP).Primary objective is to evaluate and compare clinical and radiographic outcome of partial pulpotomy following use of 2.5% Ca(OCl)₂ and 2.5% NaOCl in mature permanent mandibular molars with symptomatic irreversible pulpitis.secondary objective is to evaluate OHRQoL and pain experience after use of 2.5% Ca(OCl)₂ and 2.5% NaOCl during partial pulpotomy in permanent mandibular molars with clinical signs indicative of symptomatic irreversible pulpitis.
Eligibility Criteria
Inclusion Criteria: 1. patients aged 18-40 years 2. Mature permanent mandibular molars with extremely deep caries (caries penetrating the entire thickness of the dentine radiographically, without radiopaque zone separating lesion from the pulp) and clinical diagnosis of SIP with PAI score ≤ 2 3. Periodontally healthy teeth (probing pocket depth ≤3 mm and mobility within normal limit) 4. Patients having physical status of class 1 or 2 according to ASA classification 5. Pulpal bleeding could be controlled within 10 min following pulp amputation Exclusion Criteria: 1. Non restorable teeth 2. No pulp exposure even after complete caries excavation 3. Necrotic or partially necrotic pulp upon exposure 4. Presence of sinus tract or soft tissue swelling 5. Radiographic signs of internal or external root resorption 6. Pregnant women
Contact & Investigator
Dr Mayank Arora, MDS
PRINCIPAL INVESTIGATOR
PGIDS, Rohtak, 124001
Frequently Asked Questions
Who can join the NCT07748676 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Symptomatic Irreversible Pulpitis (SIP). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07748676 currently recruiting?
Yes, NCT07748676 is actively recruiting participants. Contact the research team at dr.arora002@gmail.com for enrollment information.
Where is the NCT07748676 trial being conducted?
This trial is being conducted at Rohtak, India.
Who is sponsoring the NCT07748676 clinical trial?
NCT07748676 is sponsored by Postgraduate Institute of Dental Sciences Rohtak. The principal investigator is Dr Mayank Arora, MDS at PGIDS, Rohtak, 124001. The trial plans to enroll 106 participants.