NCT05761197 Oropharyngeal Candidiasis (OPC) and S-ECC
| NCT ID | NCT05761197 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Temple University |
| Condition | Candida Infection |
| Study Type | OBSERVATIONAL |
| Enrollment | 70 participants |
| Start Date | 2025-01-01 |
| Primary Completion | 2028-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 70 participants in total. It began in 2025-01-01 with a primary completion date of 2028-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of severe early childhood caries (S-ECC).
Eligibility Criteria
Inclusion Criteria: * Male or female individuals at the age of 9-24-month-old * Must have at least one fully erupted tooth at baseline visit * Parent/guardian willing and able to provide informed consent * With or without a history of OPC (the study team will enroll 35 participants with and 35 participants without a history of OPC) Exclusion Criteria: * Presence of a systemic medical condition (e.g. Down syndrome etc.) * Presence of an orofacial deformity * Presence of dental caries * Use of systemic antimicrobial therapy within 30 days of the baseline visit * Presence of any condition which, in the opinion of the investigator, makes participation in the project not in the individual's best interest.
Contact & Investigator
Yuan Liu, DDS, MS, PhD
PRINCIPAL INVESTIGATOR
Temple University Kornberg School of Dentistry
Frequently Asked Questions
Who can join the NCT05761197 clinical trial?
This trial is open to participants of all sexes, aged 9 Months or older, up to 24 Months, studying Candida Infection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05761197 currently recruiting?
Yes, NCT05761197 is actively recruiting participants. Contact the research team at yuan.liu0008@temple.edu for enrollment information.
Where is the NCT05761197 trial being conducted?
This trial is being conducted at Philadelphia, United States.
Who is sponsoring the NCT05761197 clinical trial?
NCT05761197 is sponsored by Temple University. The principal investigator is Yuan Liu, DDS, MS, PhD at Temple University Kornberg School of Dentistry. The trial plans to enroll 70 participants.