| NCT ID | NCT07468019 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cairo University |
| Condition | Ectodermal Dysplasia |
| Study Type | INTERVENTIONAL |
| Enrollment | 11 participants |
| Start Date | 2026-02-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 11 participants in total. It began in 2026-02-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Ectodermal dysplasia is a rare inherited condition that affects structures derived from the ectoderm, including teeth, skin, hair, and sweat glands. Dental findings are often severe and include missing or malformed teeth and poorly developed jaw ridges. These abnormalities can significantly affect chewing, speech, facial appearance, and quality of life, especially in children and young adults. Removable dentures, particularly overdentures when some teeth are present, are commonly used to restore function and appearance in these patients because they are conservative and cost-effective. However, conventional acrylic dentures may show dimensional changes during processing, which can lead to poor denture fit, reduced retention, and lower patient satisfaction. Three-dimensional (3-D) printed dentures are a newer digital fabrication method that may reduce material shrinkage and improve denture adaptation. Despite these potential advantages, clinical evidence comparing 3-D printed and conventional overdentures in patients with ectodermal dysplasia remains limited, highlighting the need for well-designed clinical studies. The purpose of this study is to compare patient satisfaction and denture base adaptation between 3-D printed maxillary overdentures and conventional acrylic maxillary overdentures in patients with ectodermal dysplasia.
Eligibility Criteria
Inclusion Criteria: * Age must range from 10-35 years. * Must have a few remaining teeth in the maxilla. * Must will to attend all follow-ups. Exclusion Criteria: * Extreme anatomical limitations such as a large torus that requires surgical excision. * Allergy to dentures made of resins. * Pathological changes of residual ridges as recurrent or persistent ulcers, osteomyelitis and infections. 4\. Patients with medical or psychological conditions as physical disability or mental retardation that hinder cooperation in the follow up visits and answering the questionnaires.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07468019 clinical trial?
This trial is open to participants of all sexes, aged 10 Years or older, up to 35 Years, studying Ectodermal Dysplasia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07468019 currently recruiting?
Yes, NCT07468019 is actively recruiting participants. Contact the research team at yasmine.hisham@dentistry.cu.edu.eg for enrollment information.
Where is the NCT07468019 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07468019 clinical trial?
NCT07468019 is sponsored by Cairo University. The trial plans to enroll 11 participants.