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RecruitingPhase 4NCT06492512

Oral Iron Supplementation on Alternate Vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy

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Trial Parameters

ConditionIron-deficiency Anemia (IDA)
SponsorSouthern Illinois University
Study TypeINTERVENTIONAL
PhasePhase 4
Enrollment120
SexFEMALE
Min Age18 Years
Max Age45 Years
Start Date2024-12
Completion2027-07-01
Interventions
daily ferrous sulfate with an equivalent elemental iron dose of 65 mg per pillalternate day ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill

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Brief Summary

This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill.

Eligibility Criteria

Inclusion Criteria: * Pregnant patients will be enrolled at less than 30 weeks gestational age (GA) with laboratory confirmed IDA (as defined by hemoglobin under 10.5 g/dL, as well as ferritin under 15 mcg/L) Exclusion Criteria: * Patients \<18 years old, patients who have severe IDA that requires blood transfusion or IV iron infusion, patients who have other known hemoglobinopathy (such as thalassemia or sickle cell anemia) or anemia of different mechanism (such as vitamin B12 or folate deficiency), patients with ulcerative colitis, Crohn's disease, gastric ulcers, patients who have previously undergone gastric bypass surgery, patients who experience admission for antepartum bleed, have been diagnosed with abnormal placentation (i.e., placenta previa, placenta accreta, placenta increta or percreta)

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