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Recruiting NCT06501118

NCT06501118 Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients

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Clinical Trial Summary
NCT ID NCT06501118
Status Recruiting
Phase
Sponsor University of Colorado, Denver
Condition Respiratory Failure
Study Type INTERVENTIONAL
Enrollment 3,600 participants
Start Date 2024-09-01
Primary Completion 2026-07-08

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
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Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 3,600 participants in total. It began in 2024-09-01 with a primary completion date of 2026-07-08.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

A multimodal educational intervention to target an oxygen saturation target range (SpO2 90-96%) will reduce ventilator length of stay and reduce occult hypoxemia by increased awareness and adherence to a designated oxygen saturation target range.

Eligibility Criteria

Inclusion Criteria: * Admission to ICU and requiring invasive mechanical ventilation Exclusion Criteria: * Transferred patients from outside the UCHealth system\*: * Patients with pre-existing disease that requires chronic use of positive pressure ventilation delivered through a tracheostomy\*: * Pregnant women: * Prisoners * Patients receiving mechanical ventilation for less than twelve hours

Contact & Investigator

Central Contact

Carrie Higgins, BSN

✉ carrie.higgins@cuanschutz.edu

📞 720-560-3037

Principal Investigator

Neil Aggarwal, MD

PRINCIPAL INVESTIGATOR

University of Colorado, Denver

Frequently Asked Questions

Who can join the NCT06501118 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Respiratory Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06501118 currently recruiting?

Yes, NCT06501118 is actively recruiting participants. Contact the research team at carrie.higgins@cuanschutz.edu for enrollment information.

Where is the NCT06501118 trial being conducted?

This trial is being conducted at Aurora, United States.

Who is sponsoring the NCT06501118 clinical trial?

NCT06501118 is sponsored by University of Colorado, Denver. The principal investigator is Neil Aggarwal, MD at University of Colorado, Denver. The trial plans to enroll 3,600 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology