NCT07189715 Optimization of Imagery Rescripting Research Using Generative Artificial Intelligence
| NCT ID | NCT07189715 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Social Sciences and Humanities, Warsaw |
| Condition | Generalized Anxiety |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2025-06-01 |
| Primary Completion | 2025-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2025-06-01 with a primary completion date of 2025-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This pilot randomized controlled trial will investigate the feasibility and effectiveness of using generative artificial intelligence to create personalized therapeutic scripts for imagery rescripting (ImRs). Eighty participants will listen to autobiographical scenarios based on their own memories of childhood criticism and neutral events. The scenarios will be generated by the Gemini large language model and reviewed by trained experimenters. On Day 1, all participants will be exposed to both critical and neutral scenarios and randomly assigned to either an experimental group receiving an ImRs intervention or a control group receiving no therapeutic modification. Skin conductance and subjective emotional ratings will be collected during the session, with follow-up questionnaires administered one week later. In addition, cognitive-behavioral therapists will evaluate the quality of the generated scripts. The study aims to assess emotional and physiological responses to AI-generated content, compare outcomes between groups, and explore the potential of large language models in scalable psychological interventions.
Eligibility Criteria
Inclusion Criteria: * Age 18-35 * Score ≥ 8 on GAD-7 (Plummer et al., 2016) * Ability to recall at least two childhood memories involving parental criticism Exclusion Criteria: * History of prolonged physical or sexual abuse * Current psychotherapy or psychopharmacology * PTSD diagnosis (DSM-5 screening) * Substance abuse (TAPS tool)
Contact & Investigator
Stanisław Karkosz, MA
PRINCIPAL INVESTIGATOR
SWPS University
Frequently Asked Questions
Who can join the NCT07189715 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 35 Years, studying Generalized Anxiety. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07189715 currently recruiting?
Yes, NCT07189715 is actively recruiting participants. Contact the research team at skarkosz@swps.edu.pl for enrollment information.
Where is the NCT07189715 trial being conducted?
This trial is being conducted at Poznan, Poland.
Who is sponsoring the NCT07189715 clinical trial?
NCT07189715 is sponsored by University of Social Sciences and Humanities, Warsaw. The principal investigator is Stanisław Karkosz, MA at SWPS University. The trial plans to enroll 80 participants.
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