← Back to Clinical Trials
Recruiting EARLY_Phase 1 NCT05493722
Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
Trial Parameters
Condition Refractory Epilepsy
Sponsor University of Minnesota
Study Type INTERVENTIONAL
Phase EARLY_Phase 1
Enrollment 20
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-09-15
Completion 2028-01-15
All Conditions
Interventions
PS and OS stimulation order 1PS and OS stimulation order 2PS and OS stimulation order 3
Brief Summary
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.
Eligibility Criteria
Inclusion Criteria: * medically refractory epilepsy * already have a deep brain stimulator in place Exclusion Criteria: * severe dementia at investigator discretion