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Recruiting Phase 1 NCT05906433

Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis

Trial Parameters

Condition Knee Osteoarthritis
Sponsor Foundation for Orthopaedic Research and Education
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 75
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-06-01
Completion 2025-06-01
Interventions
Kenalog with bupivacaine Injection

Brief Summary

To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from procedure when postoperative status is considered success (as measured by global perceived improvement score).

Eligibility Criteria

Inclusion Criteria: 1. Patients must be 18 years of age and be able to consent for themselves. 2. OA grade Kellgren Lawrence Stage II or III. 3. Diagnosis of primary osteoarthritis. Exclusion Criteria: 1. Patients with other forms of arthritis such as inflammatory arthritis. 2. History of narcotic use for the past 6 months. 3. Kellgren Lawrence arthritis grade 1 or 4. 4. Pregnant women and prisoners.

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