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Recruiting NCT01243931

Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy

Trial Parameters

Condition Corneal Opacity
Sponsor Oregon Health and Science University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 80
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2011-06
Completion 2026-12
Interventions
OCT-guided laser phototherapeutic keratectomy

Brief Summary

Optical Coherence Tomography (OCT) machines are non-contact instruments that can measure the depth of scars and other causes of cloudiness in the front of the cornea. The purpose of this study is to determine whether OCT-guided settings for the lasers used for removal of corneal scars and other partial-thickness corneal defects result in improved vision in patients receiving these procedures.

Eligibility Criteria

Inclusion Criteria: * Patients with vision primarily limited by superficial opacities and irregularities that could be removed by PTK while leaving at least 250 µm. Exclusion Criteria: * Inability to give informed consent * Inability to maintain stable fixation for OCT imaging * Inability to commit to required visits to complete the study * Deep corneal opacities and irregularities * Cataracts, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery

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