NCT04510363 Optic Nerve Sheath Diameter, Carotid Duplex and Transcranial Duplex as a Prognostic Factor
| NCT ID | NCT04510363 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Taiwan University Hospital |
| Condition | Neurologic Dysfunction |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2019-12-17 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2019-12-17 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Optic nerve sheath diameter (ONSD) had been proved to be associated with increased intracranial pressure and can be used as one of the prognostic factors in cardiac arrest patients. It is simple, quick and can be measured repeatedly. Carotid duplex and transcranial duplex(TCD) provide rapid, noninvasive, real-time measures of cerebrovascular function. It can be used to assess the vascular territory by measuring blood flow, and to evaluate factors include brain perfusion, plaque morphology, and patency of intracranial collaterals. Hence, it could act as a crucial role in neuroprognosis in post-arrest patients. In this study, the investigator aimed to analyze the ONSD diameters, ONSD/external transverse diameter (ETD) ratio, carotid duplex and transcaranial duplex parameters in different stages of post-cardiac arrest care, demographic characteristics and resuscitation information with the neurological outcome of post-cardiac arrest patients. The ONSD diameter, and ONSD/ETD ratio were compared with age-, and sex-matched normal volunteers.
Eligibility Criteria
Inclusion Criteria: . Non-traumatic cardiac arrest adult patients achieving return of spontaneous circulation after resuscitation Exclusion Criteria: * traumatic cardiac arrests * non-traumatic arrest patients without return of spontaneous circulation after resuscitation
Contact & Investigator
Wan-Ching Lien, PhD
PRINCIPAL INVESTIGATOR
National Taiwan University Hospital
Frequently Asked Questions
Who can join the NCT04510363 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying Neurologic Dysfunction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04510363 currently recruiting?
Yes, NCT04510363 is actively recruiting participants. Contact the research team at wanchinglien@ntu.edu.tw for enrollment information.
Where is the NCT04510363 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT04510363 clinical trial?
NCT04510363 is sponsored by National Taiwan University Hospital. The principal investigator is Wan-Ching Lien, PhD at National Taiwan University Hospital. The trial plans to enroll 200 participants.