NCT05985772 Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)
| NCT ID | NCT05985772 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Rush University Medical Center |
| Condition | Meniscus Tear, Tibial |
| Study Type | INTERVENTIONAL |
| Enrollment | 140 participants |
| Start Date | 2022-04-20 |
| Primary Completion | 2029-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 140 participants in total. It began in 2022-04-20 with a primary completion date of 2029-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to determine differences in pain, functional patient reported outcomes, and objective imaging parameters following non-operative and meniscus root repair treatment. Furthermore, the long-term goal of this research proposal is to understand the natural history of meniscal root tears and their subsequent repair, in order to better determine risk factors for inferior outcomes and progression to osteoarthritis (OA).
Eligibility Criteria
Inclusion Criteria: * MRI-verified isolated tibial medial meniscus root tear * Subject must be 18 years of age or older Exclusion Criteria: * Concurrent ligamentous knee pathology requiring surgical intervention (i.e. anterior cruciate ligament tear, posterior cruciate ligament tear, posterolateral corner injury, high-grade medial collateral ligament tear), * Preoperative Kellgren-Lawrence grade of 3 or 4 * Inability to complete outcome questionnaires or comply with required postoperative imaging or MRI requirements, or medical contraindications to surgery or physical therapy. * There will be no exclusion criteria regarding body mass index (BMI) or mechanical alignment, however subjects will be stratified in groups for further analysis (BMI less and over 35 and varus alignment below and over 3º of varus). * Pregnancy * Subjects \< 18 years of age
Contact & Investigator
Jorge Chahla, MD
PRINCIPAL INVESTIGATOR
Rush University Medical Center Associate Professor and Surgeon
Frequently Asked Questions
Who can join the NCT05985772 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Meniscus Tear, Tibial. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05985772 currently recruiting?
Yes, NCT05985772 is actively recruiting participants. Contact the research team at carla_edwards@rush.edu for enrollment information.
Where is the NCT05985772 trial being conducted?
This trial is being conducted at Chicago, United States.
Who is sponsoring the NCT05985772 clinical trial?
NCT05985772 is sponsored by Rush University Medical Center. The principal investigator is Jorge Chahla, MD at Rush University Medical Center Associate Professor and Surgeon. The trial plans to enroll 140 participants.