NCT07772791 Online Cohort of Sexual and Gender Minorities: Evaluating Digital Interventions to Improve HIV Pre-Exposure Prophylaxis and Antiretroviral Treatment Uptake and Adherence
| NCT ID | NCT07772791 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Oswaldo Cruz Foundation |
| Condition | HIV Infections |
| Study Type | INTERVENTIONAL |
| Enrollment | 3,000 participants |
| Start Date | 2026-05-25 |
| Primary Completion | 2028-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 3,000 participants in total. It began in 2026-05-25 with a primary completion date of 2028-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will create and follow an online cohort of sexual and gender minorities in Brazil to better understand the use of HIV prevention and treatment strategies, particularly pre-exposure prophylaxis (PrEP) and antiretroviral treatment (ART). Participants will complete online questionnaires at the beginning of the study and every three months for one year to provide information about medication use and adherence, sexual behaviors, HIV prevention and testing, sexually transmitted infections, mental health, and experiences of discrimination in health services. Participants who are using PrEP or ART and agree to take part in the intervention will be randomly assigned to receive either a digital intervention or no digital intervention. The digital intervention will consist of weekly WhatsApp messages for six months, including reminders and information intended to support adherence to PrEP or ART. The main question of the study is whether weekly WhatsApp messages can improve adherence to PrEP or ART among sexual and gender minorities in Brazil. The study hypothesis is that participants who receive the digital intervention will have higher adherence to PrEP or ART than participants who do not receive the intervention.
Eligibility Criteria
Inclusion Criteria: male sex assigned at birth and identifying as a man, travesti, transgender person, or non-binary person; age ≥18 years; residing in Brazil; access to the internet; and self-reporting sex with a man in the past 12 months. Exclusion Criteria: incorrectly answering the attention-check questions; and incomplete responses, defined as not reaching the end of the screening questionnaire
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07772791 clinical trial?
This trial is open to male participants only, aged 18 Years or older, studying HIV Infections. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07772791 currently recruiting?
Yes, NCT07772791 is actively recruiting participants. Contact the research team at ttorres79@gmail.com for enrollment information.
Where is the NCT07772791 trial being conducted?
This trial is being conducted at Rio de Janeiro, Brazil.
Who is sponsoring the NCT07772791 clinical trial?
NCT07772791 is sponsored by Oswaldo Cruz Foundation. The trial plans to enroll 3,000 participants.
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