NCT05822141 Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure
| NCT ID | NCT05822141 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Indiana University |
| Condition | Cold Exposure |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2023-06-12 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2023-06-12 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.
Eligibility Criteria
Inclusion Criteria: * Male and female, between the ages of 18 to 40 years. * Body Mass Index (BMI) of 18.5 to 24.9 kg/m2 * Considered "moderately to highly active" by the International Physical Activity Questionnaire (IPAQ) and the Physical Activity Readiness Questionnaire (PAR-Q+) Exclusion Criteria: * History of smoking or recreational smoking, hyperlipidemia, hypertension/cardiovascular disease, diabetes, renal disease, neurological disease, metabolic disease, and bleeding disorders or delayed clotting time. * Taking SSRI's (antidepressants and anxiety medication), ADD/ADHD medication, and chronically consume pain medication (Aleve, Tylenol, CBD, etc). * Have or have had chronic disorders of the rectum (e.g., cancer, surgery, active hemorrhoids, etc.) or who currently have related acute conditions (diarrhea, constipation, etc.). * Have or have had a diagnosis of disorders related to immune suppression and/or autoimmune disease. * Are pregnant or planning on being pregnant. * Resting blood pressure of \> 130mmHg systolic or 90 mmHg diastolic. * Resting Pulse rate of \> 100 bpm. * History of regularly consuming fish oil supplements and/or regularly eating more than one fish meal per week. * Consuming more than one fish meal per week during the study.
Contact & Investigator
Timothy D Mickleborough, PhD
PRINCIPAL INVESTIGATOR
Indiana University
Frequently Asked Questions
Who can join the NCT05822141 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Cold Exposure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05822141 currently recruiting?
Yes, NCT05822141 is actively recruiting participants. Contact the research team at tmickleb@indiana.edu for enrollment information.
Where is the NCT05822141 trial being conducted?
This trial is being conducted at Bloomington, United States.
Who is sponsoring the NCT05822141 clinical trial?
NCT05822141 is sponsored by Indiana University. The principal investigator is Timothy D Mickleborough, PhD at Indiana University. The trial plans to enroll 30 participants.