NCT05364125 Olfactory Training on Smell Dysfunction Patients in HK
| NCT ID | NCT05364125 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Pamela Youde Nethersole Eastern Hospital |
| Condition | Olfaction Disorders |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2022-07-01 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2022-07-01 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
* Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. * Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery * Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. * Olfactory Training is well established treatment for sensorineural olfactory dysfunction in foreign countries. * Olfactory Training by neurological chemosensory stimulation using aromatic substances delivered via electronic portable aromatic rehabilitation (EPAR) diffuser was proved to be effective treatment in COVID-19 related olfactory dysfunction in recent Hong Kong study. * However, there is a lack of local study on the effect of Olfactory Training in other non-COVID-19 sensorineural causes of olfactory dysfunction in Hong Kong population.
Eligibility Criteria
Inclusion Criteria: * Olfactory dysfunction \> 6 months and \< 5 years Exclusion Criteria: * History of significant head injury (fracture, ICH) * History of brain surgery * History of nasal surgery * Active nasal disease * Active neurological disease * Poor premorbid status/ non-communicable patients * Mentally incompetent patients * \<18 years' old * Pregnancy * Hypersensitivity to the aromatic substance.
Contact & Investigator
Kai Chuen Fergus Wong, FRCSEd(ORL)
PRINCIPAL INVESTIGATOR
Pamela Youde Nethersole Eastern Hospital
Frequently Asked Questions
Who can join the NCT05364125 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Olfaction Disorders. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05364125 currently recruiting?
Yes, NCT05364125 is actively recruiting participants. Contact the research team at wkc568@ha.org.hk for enrollment information.
Where is the NCT05364125 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT05364125 clinical trial?
NCT05364125 is sponsored by Pamela Youde Nethersole Eastern Hospital. The principal investigator is Kai Chuen Fergus Wong, FRCSEd(ORL) at Pamela Youde Nethersole Eastern Hospital. The trial plans to enroll 80 participants.