NCT06469515 Older People's Neurocognitive Recovery After Cardiac Surgery
| NCT ID | NCT06469515 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karolinska Institutet |
| Condition | Postoperative Cognitive Dysfunction |
| Study Type | OBSERVATIONAL |
| Enrollment | 220 participants |
| Start Date | 2024-11-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 220 participants in total. It began in 2024-11-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Society is aging and advantages in anesthesia and surgery allow more complex interventions in older persons. Old age is a significant risk factor for the development of postoperative neurocognitive decline characterized by a gradual decrease in performance in several cognitive domains such as memory, attention, information processing, and executive functions, leading to problems with performing daily activities and maintaining independence and postoperative complications. The purpose of this study is to measure older persons' postoperative neurocognitive function, to detect neurocognitive decline, and to identify risk factors and difficulties in daily living as well as explore close relatives' experiences of it. We will include 220 participants ≥65 years of age undergoing planned cardiac surgery. Cognitive symptoms and signs and neurocognitive function will be assessed up to 6 months after surgery. Risk/affected factors such as delirium, functional status, recovery, depression, and healthcare-related quality of life, as well as close relative's experiences and burden, will be measured. The results will have immediate relevance for a substantial number of older persons undergoing surgery, and their close relatives, by enhancing knowledge about postoperative cognitive decline and recovery, and subsequently identifying what support needs to be implemented.
Eligibility Criteria
Inclusion Criteria: * Scheduled for elective or urgent open-heart surgery or minimally invasive cardiac surgery * Resident in the area/region for the current thoracic clinic * Able to read and understand Swedish Exclusion Criteria: * Physical, mental, and cognitive difficulties that prevent the individual from completing the cognitive tests * Undergone surgery within the last 6 months
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06469515 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Postoperative Cognitive Dysfunction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06469515 currently recruiting?
Yes, NCT06469515 is actively recruiting participants. Contact the research team at lina.bergman@ki.se for enrollment information.
Where is the NCT06469515 trial being conducted?
This trial is being conducted at Gothenburg, Sweden.
Who is sponsoring the NCT06469515 clinical trial?
NCT06469515 is sponsored by Karolinska Institutet. The trial plans to enroll 220 participants.