NCT05961800 Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks
| NCT ID | NCT05961800 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pittsburgh |
| Condition | Pain, Chronic |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2023-07-05 |
| Primary Completion | 2028-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2023-07-05 with a primary completion date of 2028-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).
Eligibility Criteria
Inclusion Criteria: * Scheduled for lumbar MBB in UPMC Pain Management clinics * Age \> 18 years old * Predominantly axial chronic low back pain at least 3 months on a daily basis * Must meet the minimum criteria for cognitive function using the PROMIS 2-item cognitive screener (\>3) * Low back pain intensity of \> 3/10 * Willing and able to receive study-related phone calls Exclusion Criteria: * History of spine surgery at the level of the lumbar MBB * Active worker's compensation or litigation claims * New pain and/or psychiatric treatments within 2 weeks of enrollment * Not fluent in English and/or not able to complete the questionnaires * Any clinically unstable systemic illness that is judged to interfere with the study
Contact & Investigator
Benedict J Alter, MD, PhD
PRINCIPAL INVESTIGATOR
University of Pittsburgh
Frequently Asked Questions
Who can join the NCT05961800 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Pain, Chronic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05961800 currently recruiting?
Yes, NCT05961800 is actively recruiting participants. Contact the research team at mam708@pitt.edu for enrollment information.
Where is the NCT05961800 trial being conducted?
This trial is being conducted at Pittsburgh, United States.
Who is sponsoring the NCT05961800 clinical trial?
NCT05961800 is sponsored by University of Pittsburgh. The principal investigator is Benedict J Alter, MD, PhD at University of Pittsburgh. The trial plans to enroll 40 participants.