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Recruiting NCT04307615

NCT04307615 O2 Versus CPAP Treatment of Patients Undergoing SIPE Therapy (OCTOPUS)

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Clinical Trial Summary
NCT ID NCT04307615
Status Recruiting
Phase
Sponsor Dalarna County Council, Sweden
Condition Swimming Induced Pulmonary Edema (SIPE)
Study Type INTERVENTIONAL
Enrollment 90 participants
Start Date 2022-07-02
Primary Completion 2027-07-15

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Oxygen + continuous positive airway pressure (CPAP)Oxygen

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 90 participants in total. It began in 2022-07-02 with a primary completion date of 2027-07-15.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

In swimming induced pulmonary edema (SIPE), there is a lack of knowledge regarding optimal treatment. The present study was designed to assess the benefit of continuous positive airway pressure (CPAP) compared to oxygen as a first line treatment of SIPE in the out-of-hospital environment.

Eligibility Criteria

Inclusion Criteria: * clinical diagnosis of swimming induced pulmonary edema (SIPE) with need of acute treatment (oxygen saturation ≤91%) * 18 years and older * informed consent Exclusion Criteria: * declined consent * suspected acute coronary syndrome * severe asthma diagnosed together with pulmonary edema where beta-agonist-inhalation is needed prior to treatment of pulmonary edema * hemodynamic instability or decreased consciousness

Contact & Investigator

Central Contact

Maria Hårdstedt, MD/PhD

✉ maria.hardstedt@regiondalarna.se

📞 46-738089464

Frequently Asked Questions

Who can join the NCT04307615 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Swimming Induced Pulmonary Edema (SIPE). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04307615 currently recruiting?

Yes, NCT04307615 is actively recruiting participants. Contact the research team at maria.hardstedt@regiondalarna.se for enrollment information.

Where is the NCT04307615 trial being conducted?

This trial is being conducted at Falun, Sweden.

Who is sponsoring the NCT04307615 clinical trial?

NCT04307615 is sponsored by Dalarna County Council, Sweden. The trial plans to enroll 90 participants.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology