NCT07477509 Northwestern Neuromuscular Disease Biorepository
| NCT ID | NCT07477509 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Northwestern University |
| Condition | Neuromuscular Diseases (NMD) |
| Study Type | OBSERVATIONAL |
| Enrollment | 2,500 participants |
| Start Date | 2026-05-01 |
| Primary Completion | 2050-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 2,500 participants in total. It began in 2026-05-01 with a primary completion date of 2050-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The primary objective of this research is to collect clinical data and tissue samples from adult patients with neuromuscular disease cared for at the Northwestern Memorial Hospital neuromuscular clinic (Lavin Building, 19th floor). This study has the following aims: Aim 1: To consent a large cohort of adult study participants with neuromuscular disorders, including but not limited to motor neuron diseases, neuropathies, neuromuscular junction disorders, and myopathies for participation in the biorepository and to collect longitudinal data on their clinical disease phenotypes. Aim 2: To obtain and store biological samples from biorepository study participants, including whole blood, plasma, serum, peripheral blood mononuclear cells \[PBMCs\], skin biopsies, and cerebrospinal fluid. Aim 3: To develop a data-sharing process to provide de-identified biorepository participant clinical data and samples to partnered investigators to expedite discovery in neuromuscular disease diagnosis and treatment.
Eligibility Criteria
Inclusion Criteria: * Undergoing evaluation for or diagnosed with a neuromuscular disorder, including but not restricted to motor neuron diseases (MNDs), neuropathies, neuromuscular junction disorders, and myopathies as a patient under the care of a provider in the Northwestern Neuromuscular Division * Provision of signed and dated informed consent form personally or via legally authorized representative (LAR) \[SOP: HRP-013\] in accordance with Good Clinical Practice (GCP), International Conference on Harmonization (ICH), and local regulations. Exclusion Criteria: * History of a bleeding disorder or current treatment with anticoagulants (e.g., Coumadin, heparin) in participating study participants that would preclude collection of CSF or skin biopsies for these sub-studies. * History of keloid formation for study participants who will undergo skin biopsy.
Frequently Asked Questions
Who can join the NCT07477509 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Neuromuscular Diseases (NMD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07477509 currently recruiting?
Yes, NCT07477509 is actively recruiting participants. Visit ClinicalTrials.gov or contact Northwestern University to inquire about joining.
Where is the NCT07477509 trial being conducted?
This trial is being conducted at Chicago, United States.
Who is sponsoring the NCT07477509 clinical trial?
NCT07477509 is sponsored by Northwestern University. The trial plans to enroll 2,500 participants.