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Recruiting NCT04471740

NCT04471740 Normal Pressure Hydrocephalus and Sleep Apnea

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Clinical Trial Summary
NCT ID NCT04471740
Status Recruiting
Phase
Sponsor University of Valencia
Condition Normal Pressure Hydrocephalus
Study Type INTERVENTIONAL
Enrollment 30 participants
Start Date 2020-07-02
Primary Completion 2029-03

Trial Parameters

Condition Normal Pressure Hydrocephalus
Sponsor University of Valencia
Study Type INTERVENTIONAL
Phase N/A
Enrollment 30
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2020-07-02
Completion 2029-03
Interventions
CSF shunt diversion

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Brief Summary

Normal-pressure hydrocephalus is associated with increases in the intracranial pressure during the night sleep. Sleep apnea also increases the intracranial pressure during the apneic spells. When patients are operated the distal part of the shunt is inserted inside the abdominal cavity, which pressure also increases during the sleep apnea episodes. this is particularly important considering that the recumbent position used to sleep further increases the intraabdominal pressure and that impairs the CSF drainage through the shunt system. The purpose of this study is to analyze the intracranial and intraabdominal pressures during the sleep, particularly during the sleep apnea episodes to see which shunt should be used, to which cavity should be drained (peritoneum or heart) and if correcting the sleep apnea has some positive result on the hydrocephalus symptoms.

Eligibility Criteria

Inclusion Criteria: * Clinical condition compatible with normal-pressure hydrocephalus Exclusion Criteria: * Cerebral vascular disease * Dementia not due to normal-pressure hydrocephalus * Parkinson's disease

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