Trial Parameters
Brief Summary
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh. The primary endpoint is the incidence of incisional hernias in both groups after one year.
Eligibility Criteria
Inclusion Criteria: * Surgery predominantly done my midline laparotomy * Age 18 years old or older * Written consent by patient/family * Midline laparotomy with delayed closure * No exclusion criteria Exclusion Criteria: * Age under 18 years * Pregnancy * Previous abdominal midline hernia mesh repair * Abdominal compartment syndrome * Linea alba closure not possible * Life expectancy under six months * Hernia in the midline with transverse diameter lager than 2 cm