NCT03895541 Noninvasive Elastography Evaluation of Myocardial Stiffness in Elderly Patients With Isolated Diastolic Heart Failure: New Diagnostic Tool?
| NCT ID | NCT03895541 |
| Status | Recruiting |
| Phase | — |
| Sponsor | French Cardiology Society |
| Condition | Cardiovascular Diseases in Old Age |
| Study Type | INTERVENTIONAL |
| Enrollment | 90 participants |
| Start Date | 2020-01-24 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 90 participants in total. It began in 2020-01-24 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The new approach propose in this protocol is based on ultrafast ultrasound and remote palpation of tissue by ultrasonic radiation pressure. Ultrafast ultrasound of biological tissues is based on an innovative ultrasound imaging approach that can image very fast soft tissue events at a rate of several thousands of frames per second and provide quantitative mapping of the elasticity of the tissues. This current project aims is to focus on myocardial rigidity in diastole to better assess the function of the heart failure.
Eligibility Criteria
Global Inclusion Criteria: * Hospitalization in cardiology services for acute pulmonary edema during heart failure * Natriuretic peptide type B ≥35 pg/ml * Echocardiographic structural alteration Specific Inclusion criteria * Group "preserved LVEF": Left ventricular Ejection Fraction ≥50% * Group "moderate alteration of LVEF": Left ventricular Ejection Fraction between 40% and 49% * Group "Systolic heart failure": Left ventricular Ejection Fraction\< 40% Global Exclusion Criteria: * Other associated lung pathology * Other heart disease * Contraindication to MRI or echocardiography gel * Pregnancy * Poor echogenicity,
Contact & Investigator
Emmanuel MESSAS, MD
PRINCIPAL INVESTIGATOR
Hopital Européen Georges Pompidou
Frequently Asked Questions
Who can join the NCT03895541 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, up to 80 Years, studying Cardiovascular Diseases in Old Age. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT03895541 currently recruiting?
Yes, NCT03895541 is actively recruiting participants. Contact the research team at emmanuel.messas@aphp.fr for enrollment information.
Where is the NCT03895541 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT03895541 clinical trial?
NCT03895541 is sponsored by French Cardiology Society. The principal investigator is Emmanuel MESSAS, MD at Hopital Européen Georges Pompidou. The trial plans to enroll 90 participants.