NCT07424066 Non-invasive Vibratory Stimulation of the Knee Muscles for the Improvement of the Somatosensory Input and Motor Performance
| NCT ID | NCT07424066 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Milano Bicocca |
| Condition | Vibration |
| Study Type | INTERVENTIONAL |
| Enrollment | 35 participants |
| Start Date | 2025-05-20 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 35 participants in total. It began in 2025-05-20 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this interventional cross-sectional study is to evaluate motor responses to non-invasive vibratory stimulation applied to the hamstring muscle tendons in healthy individuals. Knee flexion and extension efforts, in both isometric and concentric contractions, will be tested. The investigators hypothesize that vibratory stimulation causes an increase in activity in the flexor muscles (hamstrings) and a decrease in the extensor muscles (quadriceps) of the knee in all motor tasks. It follows that during knee flexion (both concentric and isometric), vibratory stimulation should cause an increase in the distance between the angular trajectories of the knee obtained with and without vibratory stimulation (with a positive sign). The increased activity of the hamstring muscles would, in fact, contribute to increasing the velocity of the flexor movement. Conversely, during extensor movements (both concentric and isometric), vibratory stimulation should reduce the instantaneous velocity of the movement, therefore causing an increase in distance (with a negative sign) between the trajectories obtained with and without stimulation. Participants will be tested using an isokinetic dynamometer and they will be asked to perform the following motor tasks in a random order: concentric knee flexion, concentric knee extension, isometric knee flexion, and isometric knee extension. The dominant limb will be tested, only. The assessment will be performed one time.
Eligibility Criteria
Inclusion Criteria: * Age equal to or greater than 18 years. Exclusion Criteria: * Neurological disorders. * Musculoskeletal injuries, including previous ones, that may compromise the execution of required movements. * Cardiorespiratory disorders.
Contact & Investigator
Cristiano Alessandro, Engineering
PRINCIPAL INVESTIGATOR
University of Milano Bicocca
Frequently Asked Questions
Who can join the NCT07424066 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Vibration. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07424066 currently recruiting?
Yes, NCT07424066 is actively recruiting participants. Contact the research team at s.scarano@auxologico.it for enrollment information.
Where is the NCT07424066 trial being conducted?
This trial is being conducted at Milan, Italy.
Who is sponsoring the NCT07424066 clinical trial?
NCT07424066 is sponsored by University of Milano Bicocca. The principal investigator is Cristiano Alessandro, Engineering at University of Milano Bicocca. The trial plans to enroll 35 participants.