← Back to Clinical Trials
Recruiting NCT04471129

Non-invasive Ventilation and High-speed Oxygen Therapy Effects on Heart Function - HiFlow-Heart Study

Trial Parameters

Condition Chronic Heart Failure
Sponsor University Hospital, Rouen
Study Type INTERVENTIONAL
Phase N/A
Enrollment 30
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2020-09-16
Completion 2026-09-16
Interventions
HFO/O2C/NIVNIV/O2C/HFO

Brief Summary

The investigators hypothesize that the airway pressures generated by High Flow Oxygen Therapy could have a beneficial impact in patients with heart failure, particularly by lowering capillary pulmonary arterial pressures. However, results compared to Non-Invasive Ventilation are difficult to predict due to the lack of data in the literature.

Eligibility Criteria

Inclusion Criteria: 1. Major patient 2. Patient who has undergone cardiac surgery with extracorporeal circulation for more than 24 hours and has been extubated for at least 6 hours. 3. Pre-operative heart failure with left ventricular ejection fraction \< 40%. 4. Invasive monitoring by pulmonary arterial catheter (Swan-Ganz) with transpulmonary thermodilution and by radial arterial catheter intended for use in the intra- and post-operative monitoring of the patient. 5. Treatment with conventional oxygen therapy (O2C) without an increase in O2 flow for more than 30 minuts, without signs of hypoxemia (SpO292%) 6. Stable hemodynamic parameters: no changes in hemodynamic parameters (arterial pressures and pulmonary and cardiac index) by more than 10% over the 30 minutes prior to inclusion and no increase in cardiotropic medication for at least 30 minutes. 7. Patient with an oxygenation rate ≤ 6L 8. For women of child-bearing age: negative pregnancy test at inclusion 9. Person who has read

Related Trials