Trial Parameters
Condition Miscarriage in First Trimester
Sponsor Chinese University of Hong Kong
Study Type OBSERVATIONAL
Phase N/A
Enrollment 150
Sex ALL
Min Age 18 Years
Max Age 45 Years
Start Date 2024-09-01
Completion 2039-08-31
Interventions
This is a routine procedure, no intervention will be provided.
Brief Summary
cfDNA is extremely useful to ascertain chromosomal causes of miscarriages at the point of miscarriage diagnosis by a simple blood test. This study aims to determine the level of cell-free DNA (cfDNA) in early pregnancy and compare the results with those of product of conception (POC) testing, in concordance with standard karyotyping.
Eligibility Criteria
Inclusion Criteria: 1. Age 18-45 years. 2. Women who attend the early pregnancy loss clinic or Patients who receive ART 3. Their partner, the biological father of the pregnancy Exclusion Criteria: * History of psychological/ psychiatric problem * Patient refusal