NCT07064421 Non-Helium Magnetoencephalography in Pediatric Refractory Epilepsy
| NCT ID | NCT07064421 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Guangzhou Women and Children's Medical Center |
| Condition | Refractory Epilepsy in Children |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-11-05 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2024-11-05 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to evaluate the effectiveness of Magnetoencephalography (MEG) in the preoperative assessment of children with refractory epilepsy, particularly in identifying the seizure focus, and to compare it with the gold standard methods of Stereo-electroencephalography (SEEG) and Electrocorticography (ECoG). The main questions this study aims to answer are: 1. How consistent is MEG with SEEG/ECoG in locating the epileptic focus in children with refractory epilepsy? 2. What is the clinical efficacy of MEG in identifying epileptic foci? Participants will: 1. Be divided into 2 groups: the case group and the control group. Participants in the case group will undergo both MEG and SEEG/ECoG for preoperative assessment, while patients in the control group will undergo only SEEG/ECoG before surgery. 2. Be followed up at 1, 3, 6, and 12 months after surgery to assess seizure control, neurological function, and quality of life.
Eligibility Criteria
Inclusion Criteria: 1. Age range: 3-18 years old; 2. Clinically diagnosed with refractory epilepsy; 3. Capable of cooperating with magnetoencephalography evaluation and recording. Exclusion Criteria: 1. Patients with serious comorbidities or neurological or psychiatric disorders that affect magnetoencephalography examination. 2. Patients using drugs that affect central nervous system function; 3. Patients who are not suitable for surgical procedures; 4. Patients with progressive neurological disorders.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07064421 clinical trial?
This trial is open to participants of all sexes, aged 3 Years or older, up to 18 Years, studying Refractory Epilepsy in Children. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07064421 currently recruiting?
Yes, NCT07064421 is actively recruiting participants. Contact the research team at 15625984282@163.com for enrollment information.
Where is the NCT07064421 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT07064421 clinical trial?
NCT07064421 is sponsored by Guangzhou Women and Children's Medical Center. The trial plans to enroll 100 participants.
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