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Recruiting NCT07222722

NIRS Monitoring in the NICU and AKI

Trial Parameters

Condition Acute Kidney Injury (AKI)
Sponsor NYU Langone Health
Study Type INTERVENTIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 24 Weeks
Max Age 30 Weeks
Start Date 2025-11
Completion 2026-04-01
Interventions
NIRS Monitoring

Brief Summary

The primary objective of this study is to describe the pattern of renal tissue oxygen saturation (SrSO2) using near-infrared spectroscopy (NIRS) in premature infants \<30 weeks gestational age. The secondary objective of this study is to evaluate prenatal and postnatal risk factors for acute kidney injury (AKI) in premature infants \<30 weeks gestational age. The investigators will also compare various rates of complications including death, length-of-stay, and prolonged duration of mechanical ventilation, among others.

Eligibility Criteria

Inclusion Criteria: * Any neonate less than 30 weeks in gestational age * Willingness and capacity of both adult parents/guardians to sign consent Exclusion Criteria: * An infant with known congenital anomalies of the kidney (i.e., grade 4 or 5 vesicoureteral reflux (VUR), posterior urethral valves, moderate or severe hydronephrosis, autosomal recessive polycystic kidney disease (ARPKD), bilateral renal agenesis or dysplasia) * Age \>30 weeks gestational age * Age \<24 weeks and \<500 grams (will be excluded due to sensitivity of skin in this vulnerable population). * Clinician's decision that NIRS is not suitable due to the patient's clinical condition

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