NCT05360186 New Cross-linked Hyaluronan Gel to Prevent Adhesion After USG-MVA: RCT
| NCT ID | NCT05360186 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Chinese University of Hong Kong |
| Condition | First Trimester Abortion |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2022-06-14 |
| Primary Completion | 2026-05-14 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2022-06-14 with a primary completion date of 2026-05-14.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of this prospective, randomized controlled study was to evaluate the effectiveness of this NCH gel in the prevention of IUA development as assessed by hysteroscopy after USG-MVA, in the treatment for first-trimester miscarriage. * To study the severity and extent of the IUA as assessed by the AFS and ESGE adhesion score in both groups of patients. * To examine the rate of complications or side effects with the NCH gel. * To assess the subsequent menstrual history and reproductive outcome in both groups of patients.
Eligibility Criteria
Inclusion Criteria: * Women 18 years old or above * No previous history of IUA/ Asherman's syndrome * No previous surgical history of EVA or dilatation or curettage or surgical termination of pregnancy or caesarean section * No previous history of therapeutic hysteroscopic surgeries * Voluntary informed consent and understanding of study Exclusion Criteria: * previous therapeutic hysteroscopic procedures (e.g. endometrial ablation, removal of fibroids or polyps, surgical correction of congenital uterine anomalies or adhesiolysis) * suspicion of molar pregnancy * genital tract malformation * suspicion of active infection or genital tract malignancy or genital tuberculosis * abnormal blood coagulation * inability to tolerate pelvic examination known * suspected intolerance of hypersensitivity to NCH gel or its derivatives * patient refusal
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05360186 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 50 Years, studying First Trimester Abortion. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05360186 currently recruiting?
Yes, NCT05360186 is actively recruiting participants. Contact the research team at elaineng@cuhk.edu.hk for enrollment information.
Where is the NCT05360186 trial being conducted?
This trial is being conducted at Hong Kong, Hong Kong.
Who is sponsoring the NCT05360186 clinical trial?
NCT05360186 is sponsored by Chinese University of Hong Kong. The trial plans to enroll 150 participants.