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Recruiting NCT05864976

NCT05864976 Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

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Clinical Trial Summary
NCT ID NCT05864976
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Glioblastoma Multiforme
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2023-12-06
Primary Completion 2030-01-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Support Vector Machine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2023-12-06 with a primary completion date of 2030-01-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is investigating the use of a computer algorithm to analyze scans of the brain before surgery to predict how a person's tumor will respond to treatment.

Eligibility Criteria

Inclusion Criteria: * Must have a radiological diagnosis of a lesion in the brain with characteristics consistent with glioblastoma multiforme. * Must be planning to undergo a pre-operative MRI. * Must be at least 18 years old. * Must be able to understand and willing to sign an IRB approved written informed consent document. Exclusion Criteria: * Contraindication to MRI. * Inability to have clinical follow-up (e.g., patient is out of town and will do follow-up elsewhere).

Contact & Investigator

Central Contact

Dimitrios Mathios, M.D.

✉ mathios@wustl.edu

📞 314-747-6146

Principal Investigator

Dimitrios Mathios, M.D.

PRINCIPAL INVESTIGATOR

Washington University School of Medicine

Frequently Asked Questions

Who can join the NCT05864976 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Glioblastoma Multiforme. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05864976 currently recruiting?

Yes, NCT05864976 is actively recruiting participants. Contact the research team at mathios@wustl.edu for enrollment information.

Where is the NCT05864976 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT05864976 clinical trial?

NCT05864976 is sponsored by Washington University School of Medicine. The principal investigator is Dimitrios Mathios, M.D. at Washington University School of Medicine. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology