| NCT ID | NCT07671950 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of British Columbia |
| Condition | Dental Neuralgia |
| Study Type | INTERVENTIONAL |
| Enrollment | 5 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 5 participants in total. It began in 2026-01-01 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective observational study will evaluate pain outcomes in patients with neuropathic dental pain (Atypical Odontalgia/Phantom Tooth Pain) who undergo directional deep brain stimulation (DBS). Participants will complete validated pain, disability, quality-of-life, and mood assessments before surgery and following DBS programming. Directional stimulation will be applied to different thalamic targets to determine whether specific stimulation settings are associated with greater pain relief. The study aims to characterize changes in pain and quality of life following DBS and to identify the stimulation target associated with the greatest reduction in neuropathic dental pain.
Eligibility Criteria
Inclusion Criteria: * Age 19 to 80 years. * Diagnosis of Atypical Odontalgia (AO) (also known as neuropathic dental pain). * Receiving deep brain stimulation (DBS) treatment for AO due to inadequate response to conventional therapies, including: Pharmacological therapies, and/or Local anesthetics, corticosteroid injections, or nerve blocks. * Able and willing to provide informed consent. Exclusion Criteria: * Refusal or inability to provide informed consent. * Known major depression. * Acute psychosis.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07671950 clinical trial?
This trial is open to participants of all sexes, aged 19 Years or older, up to 80 Years, studying Dental Neuralgia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07671950 currently recruiting?
Yes, NCT07671950 is actively recruiting participants. Contact the research team at danielle.pietram@ubc.ca for enrollment information.
Where is the NCT07671950 trial being conducted?
This trial is being conducted at Vancouver, Canada.
Who is sponsoring the NCT07671950 clinical trial?
NCT07671950 is sponsored by University of British Columbia. The trial plans to enroll 5 participants.