NCT05845333 Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women
| NCT ID | NCT05845333 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Mind Research Network |
| Condition | Stimulant Abuse |
| Study Type | OBSERVATIONAL |
| Enrollment | 334 participants |
| Start Date | 2022-08-01 |
| Primary Completion | 2027-05-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 334 participants in total. It began in 2022-08-01 with a primary completion date of 2027-05-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Substance use disorders and psychopathy are serious and costly mental health issues. Psychopathy is known to be associated with aberrant moral decision making and there is considerable interest in determining whether substance use disorders lead to impairments in these same cognitive processes. Recent large-scale research initiatives in forensic settings have begun to identify substance abuse and psychopathy-related disruption in the neural mechanisms involved in moral decision-making processes, and associations between these neural networks and future relapse and antisocial behavior. Here the investigators extend prior work (with incarcerated men) to examine these issues among incarcerated women in order to better understand sex differences. This project addresses the overall lack of neurocognitive research in criminal offenders with substance use disorders, thereby focusing on a major public health issue in an underserved and understudied population.
Eligibility Criteria
Inclusion Criteria: * Biological sex is female * Intelligence Quotient 70 or higher * Reading level 5th grade or higher * Able to speak and understand English Exclusion Criteria: * Uncorrectable auditory or visual deficits * Currently pregnant * MRI contraindication * Central nervous system disease * Current major medical condition * Hypertension with complications (e.g., stroke) * Diabetes with complications * Lifetime history of psychotic disorder * Self-report of psychotic disorder (with psychiatric hospitalization) in first degree relative * Drug use in past three months (Healthy controls only): * History of arrest * Substance use beyond light alcohol or marijuana use * Currently taking psychotropic medications
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05845333 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 70 Years, studying Stimulant Abuse. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05845333 currently recruiting?
Yes, NCT05845333 is actively recruiting participants. Contact the research team at charenski@mrn.org for enrollment information.
Where is the NCT05845333 trial being conducted?
This trial is being conducted at Albuquerque, United States.
Who is sponsoring the NCT05845333 clinical trial?
NCT05845333 is sponsored by The Mind Research Network. The trial plans to enroll 334 participants.