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Recruiting NCT06111898

Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants

Trial Parameters

Condition Premature Birth
Sponsor University Hospital, Geneva
Study Type OBSERVATIONAL
Phase N/A
Enrollment 348
Sex ALL
Min Age 35 Weeks
Max Age 1 Year
Start Date 2023-10-10
Completion 2026-03-31
Interventions
No Intervention

Brief Summary

This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied. In addition, the evolution of these neuro-biomechanical determinants during the first year of life will be investigated. The examinations are planned for a group of high-risk infants (e.g. premature birth, cases of asphyxia, etc.) compared with a group of infants with typical development.

Eligibility Criteria

Inclusion \& exclusion criteria for group of high-risk infants: * Infants born before or at 28 weeks of gestation * Infants born after 28 weeks of gestation and with brain injury. * A term birth with the clinical diagnosis of asphyxia (ischemic event with hypothermia) or neonatal stroke * Exclusion in case of genetic syndrome, or lower limb pathology (e.g. spina bifida) Inclusion \& exclusion criteria for group of typically developing children: * Born at a gestational age above 37 weeks * Birth weight between P10 and P90 * Head circumference between P10 and P90 * Ph \>7.1 * Exclusion in case of genetic syndrome, lower limb pathology and/or brain malformations

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