NCT05670093 Neural Pressure Support, Synchrony and Respiratory Muscle Unloading
| NCT ID | NCT05670093 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karolinska Institutet |
| Condition | Acute Respiratory Failure |
| Study Type | INTERVENTIONAL |
| Enrollment | 22 participants |
| Start Date | 2022-05-17 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 22 participants in total. It began in 2022-05-17 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In this study patients who are intubated and on ventilator for more than 24h will be ventilated at three different level of support in Pressure Support and Neural Pressure Support to study patient-ventilator synchrony and muscle unloading.
Eligibility Criteria
Inclusion Criteria: -Patients intubated for more than 24 hours in the weaning phase from the ventilator. Exclusion Criteria: * bleeding disorders (PK INR\>1,5 or APTT\>50s or platelet count \<50000/µL) * unstable circulation (requiring high vasopressor dose, for example Noradrenalin \>0,2µg/kg/min) * severe lung disease (PFI ≤ 13,3 kPa) * fever\> 38,5°C * pregnancy.
Contact & Investigator
Francesca Campoccia Jalde
PRINCIPAL INVESTIGATOR
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Frequently Asked Questions
Who can join the NCT05670093 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Respiratory Failure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05670093 currently recruiting?
Yes, NCT05670093 is actively recruiting participants. Contact the research team at francesca.campoccia-jalde@regionstockholm.se for enrollment information.
Where is the NCT05670093 trial being conducted?
This trial is being conducted at Solna, Sweden.
Who is sponsoring the NCT05670093 clinical trial?
NCT05670093 is sponsored by Karolinska Institutet. The principal investigator is Francesca Campoccia Jalde at Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.. The trial plans to enroll 22 participants.