NCT05607381 Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
| NCT ID | NCT05607381 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Utah |
| Condition | Low Back Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2022-11-30 |
| Primary Completion | 2027-04-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2022-11-30 with a primary completion date of 2027-04-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based therapy for patients with opioid-treated chronic low back pain.
Eligibility Criteria
Inclusion Criteria: 1\) men/women 18-65 years of age; 2) current chronic low back pain classified according to the NIH Pain Consortium task force research standards for chronic low back pain (pain on at least half the days in the past 6 months); usual back pain ≥3 on 0-10 scale with opioid medication; and 4) current use of prescription opioids for ≥3 months. Exclusion Criteria: 1\) Prior experience with MBSR, MBCT, MORE, or extensive involvement in any standardized meditation training, 2) current cancer diagnosis, 3) suicide intent or attempt in the past 30 days, 4) psychosis or moderate/severe non-opioid substance use disorder in past 6 months; 5) persons with any electronic objects or certain metal objects in their head or body that are incompatible with MRI; 6) those who have had an abnormal brain MRI in the past; 7) those unable to lie still on their back for 1 to 1.5 hours; and 8) pregnancy.
Contact & Investigator
Eric Garland, PhD
PRINCIPAL INVESTIGATOR
University of Utah
Frequently Asked Questions
Who can join the NCT05607381 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Low Back Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05607381 currently recruiting?
Yes, NCT05607381 is actively recruiting participants. Contact the research team at eric.garland@socwk.utah.edu for enrollment information.
Where is the NCT05607381 trial being conducted?
This trial is being conducted at La Jolla, United States, Salt Lake City, United States.
Who is sponsoring the NCT05607381 clinical trial?
NCT05607381 is sponsored by University of Utah. The principal investigator is Eric Garland, PhD at University of Utah. The trial plans to enroll 150 participants.