NCT06214923 Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
| NCT ID | NCT06214923 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Maryland, Baltimore |
| Condition | Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 78 participants |
| Start Date | 2024-04-09 |
| Primary Completion | 2026-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 78 participants in total. It began in 2024-04-09 with a primary completion date of 2026-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Eligibility Criteria
Inclusion Criteria: * Age (18-88 years) * English speaker (written and spoken) * Temporal Mandibular Disorder (TMD) for at least 3 months * TMD Grade Chronic Pain Scale (GCPS) ≥ 0 Exclusion Criteria: * Present or past degenerative neuromuscular disease * Cardiovascular, neurological diseases, pulmonary abnormalities, kidney disease, liver disease, history of cancer within past 3 years * Cervical pain (e.g. stenosis, radiculopathy) * Any personal (or family first degree) history of mania, schizophrenia, or other psychoses * Severe psychiatric condition (e.g. schizophrenia, bipolar disorders, autism) leading to hospitalization within the last 3 years. * Use of Antipsychotics (e.g., Risperdal, Ability and clozaril)Lifetime alcohol/drug dependence or alcohol/drug abuse in past 3 months * Pregnancy or breast feeding * Color-blindness * Impaired or uncorrected hearing * Non-dominant hand * Any facial trauma that has occurred in the last 6 weeks * History of a severe facial trauma in the last 2-3 months * Conditions that would interfere with the VR mask placement (e.g. trauma, burn, infection) * Known history of severe motion sickness * Non-removable head cover, artificial hair, certain types of braids or dreadlocks * History of fainting * History of angioedema * Failed drug test (testing for opiates, cocaine, methamphetamines, and amphetamines)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06214923 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 88 Years, studying Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06214923 currently recruiting?
Yes, NCT06214923 is actively recruiting participants. Contact the research team at NRSCollocaLab@umaryland.edu for enrollment information.
Where is the NCT06214923 trial being conducted?
This trial is being conducted at Baltimore, United States, Baltimore, United States.
Who is sponsoring the NCT06214923 clinical trial?
NCT06214923 is sponsored by University of Maryland, Baltimore. The trial plans to enroll 78 participants.