NCT06701851 Neural Correlates of Movement Disorders Associated With PRRT2 Related Paroxysmal Kinesigenic Dyskinesia - an Ancillary Study of AMEDYST Research
| NCT ID | NCT06701851 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Institut National de la Santé Et de la Recherche Médicale, France |
| Condition | Paroxysmal Dyskinesia |
| Study Type | INTERVENTIONAL |
| Enrollment | 1 participants |
| Start Date | 2025-01-21 |
| Primary Completion | 2028-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1 participants in total. It began in 2025-01-21 with a primary completion date of 2028-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main objective of this study is to investigate in real-time the neuronal correlates of paroxysmal dyskinesia episodes related to the PRRT2 mutation within this subgroup of patients (who can control paroxysmal dyskinesia episodes), and more specifically, the pathological role of the reciprocal influence between the striatum and the cerebellum in paroxysmal dyskinesia episodes.
Eligibility Criteria
Inclusion Criteria: Male or female Individuals with dystonic disease carrying a PRRT2 mutation and demonstrating the ability to control paroxysmal dyskinesia episodes. Affiliated with a health insurance system or a beneficiary of such a system. Individuals aged 18 to 75 years. Signature of informed consent Exclusion Criteria: Individuals under guardianship. Individuals not residing in France. Individuals unable to comply with protocol constraints (compliance with visit schedules and ability to perform required tasks). Individuals undergoing an exclusion period for another research study. Contraindications to MRI
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06701851 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Paroxysmal Dyskinesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06701851 currently recruiting?
Yes, NCT06701851 is actively recruiting participants. Contact the research team at emmanuel.flamand-roze@psl.aphp.fr for enrollment information.
Where is the NCT06701851 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT06701851 clinical trial?
NCT06701851 is sponsored by Institut National de la Santé Et de la Recherche Médicale, France. The trial plans to enroll 1 participants.