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Recruiting NCT06469580

Neonatologist-performed Lung Ultrasound (NPLUS) to Guide Respiratory Therapy to Prevent Extubation Failure

◆ AI Clinical Summary

This study tests whether using ultrasound of the lungs (a safe imaging technique) can help doctors better decide when babies are ready to stop using breathing machines and can breathe on their own. The ultrasound may help doctors take action earlier if a baby is having trouble breathing after the machine is removed.

Key Objective: The potential benefit is that lung ultrasound could help prevent babies from needing to go back on breathing machines after extubation by detecting problems earlier.

Who to Consider: Parents of newborns who are being treated with mechanical ventilation and are approaching the point of being ready to be weaned off the breathing machine should consider this trial.

Trial Parameters

Condition Neonatal Disease
Sponsor Medical University of Graz
Study Type INTERVENTIONAL
Phase N/A
Enrollment 40
Sex ALL
Min Age 1 Minute
Max Age 6 Months
Start Date 2024-06-01
Completion 2025-05
Interventions
NPLUS (neonatologist performed lung ultrasound)

Brief Summary

The objective of the study is to evaluate the role of neonatologist-performed lung ultrasound (NPLUS) after weaning from invasive mechanical ventilation and extubation. Our aim is to study the diagnostic accuracy of NPLUS and investigate whether LUS leads to earlier actions before clinical deterioration and hence prevents extubation failure.

Eligibility Criteria

Inclusion Criteria: * All preterm and full-term neonates receiving invasive mechanical ventilation at the Division of Neonatology of the Medical University of Graz AND * Written informed consent was obtained from parents prior to extubation Exclusion Criteria: none

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