NCT07434596 Neonatal Intestinal Obstruction: Prenatal Factors and Postnatal Outcomes
| NCT ID | NCT07434596 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Meyer Children's Hospital IRCCS |
| Condition | Intestinal Obstruction |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-03-11 |
| Primary Completion | 2026-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2025-03-11 with a primary completion date of 2026-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Neonatal intestinal obstruction is one of the most common surgical emergencies in newborns. In some cases, signs of possible intestinal obstruction can already be detected during pregnancy through prenatal ultrasound. However, not all prenatal ultrasound findings accurately predict whether a newborn will truly have an intestinal obstruction after birth. The purpose of this retrospective observational study is to evaluate which prenatal ultrasound findings are most strongly associated with confirmed intestinal obstruction after birth. In particular, the study aims to identify a specific cutoff value for fetal bowel dilation that best predicts postnatal intestinal obstruction. Other prenatal ultrasound features, such as excess amniotic fluid (polyhydramnios), ascites, echogenic bowel, and other abdominal findings, will also be analyzed. The study will include newborns with a prenatal suspicion of intestinal obstruction who were evaluated at Meyer Children's Hospital between January 2016 and December 2024. Researchers will review existing medical records and ultrasound data. No additional tests or interventions will be performed for study purposes. The results of this study may help improve prenatal counseling, optimize delivery planning in specialized centers, and support early postnatal management of newborns at risk for intestinal obstruction.
Eligibility Criteria
Inclusion Criteria: * Neonates from singleton pregnancies with prenatal ultrasound suspicion of intestinal obstructive pathology * Availability of complete postnatal follow-up data Exclusion Criteria: * Missing delivery data * Missing prenatal ultrasound data
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07434596 clinical trial?
This trial is open to participants of all sexes, aged 0 Days or older, up to 28 Days, studying Intestinal Obstruction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07434596 currently recruiting?
Yes, NCT07434596 is actively recruiting participants. Contact the research team at antonino.morabito@unifi.it for enrollment information.
Where is the NCT07434596 trial being conducted?
This trial is being conducted at Florence, Italy.
Who is sponsoring the NCT07434596 clinical trial?
NCT07434596 is sponsored by Meyer Children's Hospital IRCCS. The trial plans to enroll 60 participants.