NCT05413291 Natural History Protocol for Movement Disorders
| NCT ID | NCT05413291 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Institute of Neurological Disorders and Stroke (NINDS) |
| Condition | Movement Disorder |
| Study Type | OBSERVATIONAL |
| Enrollment | 4,000 participants |
| Start Date | 2022-10-17 |
| Primary Completion | 2030-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 4,000 participants in total. It began in 2022-10-17 with a primary completion date of 2030-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Background: A movement disorder is a condition that causes a person s body to move in ways that are not normal. There are different types. Some disorders cause movements people can t control, such as tics or shaking. Some cause reduced or slow movements. Movement disorders can cause disability in people. Sometimes members of the same family will have the same disorder. Researchers want to learn more about how people develop these disorders. This research could lead to better treatments. Objective: This natural history study will collect data on people with different types of movement disorders. It will also collect data on their family members. The data will support further research. Eligibility: Children and adults aged 2 years and older who have a movement disorder. Family members of people with movement disorders are also needed. Design: Participants will undergo screening. They will have a physical exam. Researchers will look at their existing medical images. Any photographs or videos of their movements will also be reviewed. Most participants will come to the NIH clinic for only 1 visit. They will answer questions about their condition. They will have normal tests used to diagnose their condition. They may have blood tests and different types of imaging scans. They may have tests to see how well their nerves function. The tests used will depend on the type of disorder they have. Family members will have some of the same tests as people with disorders. Participants will not receive any new treatments. Some participants may be asked to return for a follow-up visit. Up to 4000 people may participate.
Eligibility Criteria
* INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Stated willingness to comply with all study procedures and availability for the duration of the study * Male or female, aged 2 and above * Either one of these: * Have or suspected to have a diagnosis of a movement disorder. * Family member of someone who has or is suspected of having a diagnosis of a movement disorder. * Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document. EXCLUSION CRITERIA: An individual who meets the following criteria will be excluded from participation in this study: -Being \< 2 years old.
Contact & Investigator
Debra J Ehrlich, M.D.
PRINCIPAL INVESTIGATOR
National Institute of Neurological Disorders and Stroke (NINDS)
Frequently Asked Questions
Who can join the NCT05413291 clinical trial?
This trial is open to participants of all sexes, aged 2 Years or older, up to 100 Years, studying Movement Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05413291 currently recruiting?
Yes, NCT05413291 is actively recruiting participants. Contact the research team at vivian.koo@nih.gov for enrollment information.
Where is the NCT05413291 trial being conducted?
This trial is being conducted at Bethesda, United States.
Who is sponsoring the NCT05413291 clinical trial?
NCT05413291 is sponsored by National Institute of Neurological Disorders and Stroke (NINDS). The principal investigator is Debra J Ehrlich, M.D. at National Institute of Neurological Disorders and Stroke (NINDS). The trial plans to enroll 4,000 participants.