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Recruiting NCT06546137

NCT06546137 National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

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Clinical Trial Summary
NCT ID NCT06546137
Status Recruiting
Phase
Sponsor Hospital do Coracao
Condition Cardiomyopathy, Hypertrophic
Study Type OBSERVATIONAL
Enrollment 1,211 participants
Start Date 2025-04-30
Primary Completion 2026-08-31

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type OBSERVATIONAL
Interventions
whole genome sequencing

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,211 participants in total. It began in 2025-04-30 with a primary completion date of 2026-08-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this observational study is to develop a registry of Brazilian patients with hereditary cardiovascular diseases, combining clinical and genomic data. The main questions it aims to answer are: Which genes are most commonly affected? What is the frequency of these genetic alterations in our population? Participants will be interviewed in routine medical care visits and their DNA will be sequenced.

Eligibility Criteria

Inclusion Criteria: * Clinical diagnosis of a hereditary cardiovascular disease according to current clinical guidelines * Agree to receive genetic counseling * Sign informed consent form * Provide the information required in the case report form Exclusion Criteria: * Signature absent from informed consent form * Inadequate buccal swab (sample may be collected twice)

Contact & Investigator

Central Contact

Adriana Bastos Carvalho, MD PhD

✉ carvalhoab@biof.ufrj.br

📞 +552130372105

Frequently Asked Questions

Who can join the NCT06546137 clinical trial?

This trial is open to participants of all sexes, studying Cardiomyopathy, Hypertrophic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06546137 currently recruiting?

Yes, NCT06546137 is actively recruiting participants. Contact the research team at carvalhoab@biof.ufrj.br for enrollment information.

Where is the NCT06546137 trial being conducted?

This trial is being conducted at Rio Branco, Brazil, Maceió, Brazil, Macapá, Brazil, Fortaleza, Brazil and 11 additional locations.

Who is sponsoring the NCT06546137 clinical trial?

NCT06546137 is sponsored by Hospital do Coracao. The trial plans to enroll 1,211 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology