NCT01496625 National Eye Institute Biorepository for Retinal Diseases
| NCT ID | NCT01496625 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Eye Institute (NEI) |
| Condition | Age-Related Macular Degeneration |
| Study Type | OBSERVATIONAL |
| Enrollment | 650 participants |
| Start Date | 2012-06-18 |
| Primary Completion | — |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 650 participants in total. It began in 2012-06-18.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Background: \- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some people respond to treatment while others do not. Researchers want to collect physical samples and personal data to develop a National Eye Institute database. Objectives: \- To collect health information and blood and tissue samples from people with and without eye diseases, to be used in research studies. Eligibility: * Individuals at least 2 years of age with different types of eye disease. * Healthy volunteers with no history of eye disease. Design: * Participants may be recruited from National Eye Institute studies or may be referred from other sources. * Participants will be screened with a physical exam and medical history. They will also have a full eye exam. Questions will be asked about family medical history, especially about eye disease. * Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and urine, may be collected as needed. Adult participants may also provide a skin sample. * Tissue or fluid from eye collected as part of eye care or treatment may also be added to the database. * No treatment will be provided as part of this study.
Eligibility Criteria
* INCLUSION CRITERIA: Participants will be eligible if they: * Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children. * Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected control suitable for comparison to participants with various retinal diseases, particularly AMD and diabetic retinopathy (taking into account matching factors such as age and past ocular history). EXCLUSION CRITERIA: Participants will not be eligible if they: * Are unable or unwilling to give informed consent that includes collection and study of at least one peripheral blood sample. * Are unable or unwilling to give informed consent that includes use of NIH medical records and clinical samples for research. * Have a systemic disease that compromises the ability to provide adequate ophthalmologic examination or treatment.
Contact & Investigator
Tiarnan DL Keenan, M.D.
PRINCIPAL INVESTIGATOR
National Eye Institute (NEI)
Frequently Asked Questions
Who can join the NCT01496625 clinical trial?
This trial is open to participants of all sexes, aged 2 Years or older, up to 120 Years, studying Age-Related Macular Degeneration. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT01496625 currently recruiting?
Yes, NCT01496625 is actively recruiting participants. Contact the research team at sheena.jose@nih.gov for enrollment information.
Where is the NCT01496625 trial being conducted?
This trial is being conducted at Bethesda, United States.
Who is sponsoring the NCT01496625 clinical trial?
NCT01496625 is sponsored by National Eye Institute (NEI). The principal investigator is Tiarnan DL Keenan, M.D. at National Eye Institute (NEI). The trial plans to enroll 650 participants.