NCT07395778 Nasojejunal Feeding Versus Oral Feeding Following Endoscopic Drainage of Walled Off Pancreatic Necrosis
| NCT ID | NCT07395778 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Post Graduate Institute of Medical Education and Research, Chandigarh |
| Condition | Walled Off Pancreatic Necrosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-10-18 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-10-18 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this randomized control trial is to assess whether nasojejunal feed is better than oral nutrition in patients who are undergoing endoscopic cystogastrostomy of walled off necrosis following acute pancreatitis. It will also try to answer, the incidence of infections and feed tolerance. The main question it tries to answer is 1. whether nasojejunl feed is better than oral feed in patients undergoing endoscopic cystogastrostomy in walled off necrosis following acute pancreatitis 2. How much infections they develop, whether they are able to tolerate the feed, weight gain and reintervention rates in each group
Eligibility Criteria
Inclusion Criteria: 1. Patients of acute pancreatitis (AP) with 18-75 years of age 2. Patients with symptomatic WON requiring EUS guided transluminal drainage 3. Provision of written informed consent Exclusion Criteria: 1. Patients with collection not amenable for EUS guided drainage (distance of WON \>1 cm from the gastrointestinal lumen) 2. Known malignancy or immunocompromised state 3. Previous upper gastrointestinal(GI) surgery interfering with absorption 4. Active GI bleeding 5. GI obstruction, ileus or persistent vomiting 6. Patients moribund to undergo endoscopic procedure (Glasgow coma scale \<8 or patients on ventilatory support) 7. Patients with irreversible coagulopathy like platelets \<50,000/mm3 and/or INR\>1.5 8. Pregnant or lactating female
Contact & Investigator
Surender Singh Rana, Professor
PRINCIPAL INVESTIGATOR
Post Graduate Institute of Medical Education and Research, Chandigarh
Frequently Asked Questions
Who can join the NCT07395778 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Walled Off Pancreatic Necrosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07395778 currently recruiting?
Yes, NCT07395778 is actively recruiting participants. Contact the research team at drsaurabhkrsingh@gmail.com for enrollment information.
Where is the NCT07395778 trial being conducted?
This trial is being conducted at Chandigarh, India.
Who is sponsoring the NCT07395778 clinical trial?
NCT07395778 is sponsored by Post Graduate Institute of Medical Education and Research, Chandigarh. The principal investigator is Surender Singh Rana, Professor at Post Graduate Institute of Medical Education and Research, Chandigarh. The trial plans to enroll 50 participants.