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Recruiting NCT05920330

NCT05920330 Nasal Obstruction and Olfactory Losses

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Clinical Trial Summary
NCT ID NCT05920330
Status Recruiting
Phase
Sponsor Ohio State University
Condition Nasal Obstruction
Study Type INTERVENTIONAL
Enrollment 330 participants
Start Date 2023-01-25
Primary Completion 2027-07-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
Nasal Plug

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 330 participants in total. It began in 2023-01-25 with a primary completion date of 2027-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to these symptoms. The proposed study aims to develop novel clinical tools to better evaluate and relieve patients' nasal obstructive symptoms and to enable patients and clinicians to make more informed, personalized decisions regarding treatment strategy.

Eligibility Criteria

Inclusion Criteria: 1. Smell Loss complaints 2. Nasal Obstruction Exclusion Criteria: 1. Congenital olfactory losses 2. Nasal polyps, blocking the olfactory cleft 3. Significant atrophy 4. Cystic fibrosis 5. Wegeners or any other connective tissue disorder 6. Head trauma

Contact & Investigator

Central Contact

Veronica Formanek, BS

✉ Veronica.Formanek@osumc.edu

📞 630-501-8168

Principal Investigator

Kai Zhao, Ph.D

PRINCIPAL INVESTIGATOR

Associate Professor

Frequently Asked Questions

Who can join the NCT05920330 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Nasal Obstruction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05920330 currently recruiting?

Yes, NCT05920330 is actively recruiting participants. Contact the research team at Veronica.Formanek@osumc.edu for enrollment information.

Where is the NCT05920330 trial being conducted?

This trial is being conducted at Columbus, United States.

Who is sponsoring the NCT05920330 clinical trial?

NCT05920330 is sponsored by Ohio State University. The principal investigator is Kai Zhao, Ph.D at Associate Professor. The trial plans to enroll 330 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology